Pathology (laboratory)

 

The Pathology lab has a central role in both clinical and translational research by offering high-level experienced diagnostic expertise and collecting tumor samples from all body sites in a Tumor Bank. The laboratory facilitates access, characterization and selection of tumor tissue for all cancer research groups.

Research topics

  1. General
    a. The tumor bank is member of an interuniversitary consortium with its general data base at the National Cancer Registry. Over 2600 tumors and associated non-tumoral tissue samples are prospectively stored according to the Tubafrost recommendations. The clinical data, tumor diagnostic and prognostic elements are registered. Tissue DNA and RNA extraction and quality assessment are performed.
    b. Archival material from routine clinical pathology diagnosis is available for targeted research applications.
    c. The Pathologists in the lab are involved in different oncology research groups offering expertise in morphological support of the research activity.
    d. The lab offers validation of new diagnostic tests from research to clinical application.
  2.  Study of pathological characteristics, immunohistochemical markers and molecular markers predicting response to radio/chemotherapy and determining prognosis in oncology (Prof Dr Anne Hoorens)
  3.  Angiogenesis in thyroid carcinoma (Dr Caroline Geers)

Clinical trials

  1. Performance evaluating protocol digene HPV genotypingPS test (Qiagen)
  2. The Pathology lab is involved as investigator in over 35 currently running clinical trials in cancer.